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RESSTORE: a Multicentric and European clinical trial 2015-2020

RESSTORE, REgenerative Stem cell therapy for STroke in Europe, is a multicentric project in Personalising health and care (PHC) area financed by the European Commission H2020 programme. The RESSTORE project is focused on the assessment of the efficacy of intravenous cell therapy to improve recovery and/or compensation after ischemic stroke. The RESSTORE consortium consists of 28 partners, including 23 clinical centers, 5 cell therapy units, 5 experimental laboratories, 1 Clinical Research Organisation. The project, co-coordinated by Dr Olivier Detante (CHU Grenoble, France) and Pr Exuperio DIEZ TEJEDOR (SERMAS, Madrid, Spain), will recruit 400 patients from the Czech Republic, Finland, France, Spain, Scotland and deliver new knowledge on the fast growing area of regenerative medicine. The project started in September 2015 and will receive funding from the European Commission for 5 years.

Disclaimer: The RESSTORE project and associated cell therapy is an experimental study with a well defined scientific scope which adheres to the most stringent regulatory and ethical requirements. Patient recruitment follows a strict procedure (inclusion/exclusion criteria according to a large range of variables), applied by clinical experts in all partnering centres to meet the boundaries defined in the study protocol. 

The RESSTORE cellular therapy is (as one of the major inclusion criterias amongst several others) specifically targeted to individuals who suffered from a particular type of stroke (hemispheric, ischemic stroke) and who can be enroled in the study after 1-4 days post-stroke

NCT number: NCT02849613 and EudraCT number: 2016-001902-40

Latest news

RESSTORE 2nd Annual Meeting, Seville, 6th & 7th November 2017

RESSTORE 2nd Annual Meeting took place in Seville on 6th and 7th November 2017. Workpackages progress was presented to the whole consortium and workshops on cell production, clinical trial and experimental work were organised. 

RESSTORE clinical meeting on 16th May 2017, Prague

First RESSTORE progress meeting

The first RESSTORE progress meeting took place on the 6th and 7th of October 2016 in the Chateau de Montchât, in Lyon (France). This event allowed partners to follow all current ongoing activities on the project, review in-depth the clinical trial protocol with the input of expert clinicians as well as discuss any potential bottlenecks that should be overcome. The project is on track - all authorisations required to launch the clinical trial are being gathered while all necessary links between all participating clinical centers, cell manufacturing groups and Medfiles -the CRO in charge of all operationnel aspects of the trial - are now in place.


ABN – Association of British Neurologists Annual Meeting 2018, Birmingham (UK)

Wednesday, May 9, 2018 to Friday, May 11, 2018

The Association of British Neurologists Annual Meeting 2018 will explore the spectrum of acute neurological care delivery throughout the UK.

ESOC – 4th European Stroke Organisation Conference, Gothenburg (Sweden)

Wednesday, May 16, 2018 to Friday, May 18, 2018

The ESOC 2018 will facilitate learning, discussion, and exchange among European and international stroke specialists. Guided by the motto “The Voice of Stroke in Europe,” at the Conference will be presented the latest clinical trials and developments in all areas of stroke management, treatment and prevention.